MRC PhD student
Level of study: PhD
Title: Mycobacterium tuberculosis dynamics in a high incidence area in Cape Town.
Background: University of Stellenbosch
Project Description
Mycobacterium tuberculosis is responsible for considerable morbidity and mortality worldwide. More than two million people die each year. The aim of the study is to determine the emergency of different Mtb strain families in the Western Cape, South Africa.
Progress made thus far:
Sputum cultures were genotyped using international standardized RFLP method. Strain families were identified using IS6110 similarity index of more than 65%. Isolates were genotyped using IS6110 fingerprinting technique. A total of 37 strain families were identified during 1993 to 2004. F29 and F11 have been found to be the largest strain families responsible for two outbreaks infecting more than 150 people.
Supervisors: Prof Paul van Helden
Mentor: Prof Rob Warren
MRC Unit: Centre for Molecular and Cellular Biology |
