Job opportunities

Job opportunities

Thank you for your interest in joining the SAMRC team.

Dedicated to improving the nation’s health and quality of life, the SAMRC relies on the knowledge, skills and professionalism of our staff.

Successful candidates have the opportunity to work with some of the world’s most innovative researchers and partner institutions to ultimately build a healthy nation for all.

Positions currently available for applications:

Finance Manager - 23 January 2020 23:59
HIV Prevention Research Unit, Durban
Key to the role of the Finance Manager (FM) is financial management. The position manages, develops and controls, to ensure the integrity and timely provision of financial management and corporate reporting, including budgeting, forecasting and management of the Finance Office.
Corporate Risk & Assurance Specialist - 24 January 2020 23:59
Enterprise Risk Management, Cape Town
The Enterprise Risk Management (ERM) Office has a vacancy for a suitably qualified and experienced Corporate Risk & Assurance Specialist. The incumbent will support the Office in developing, implementing and managing the SAMRC corporate risk, assurance & policy management functions to assist in actively reducing risk exposures & exploit opportunities, and assist with ensuring that the SAMRC complies with legislative requirements.
Post-Doctoral Scholarship for 2020-2022 - 12 February 2020 23:59
Biomedical Research and Innovation Platform, Parow, Cape Town
A research collaboration between the South African Medical Research Council (SAMRC), National Health Laboratory Service (NHLS)/Walter Sisulu University (WSU) and University of Autónoma de Madrid (UA) has made available a 2- year Post-Doctoral position. The Post-Doctoral position will form part of a multi-disciplinary NRF-CPRR funded study that aims to elucidate the role inter-individual genetic variation plays in the development of uncontrolled hypertension. The primary objective of this study is to identify genetic variants that may facilitate the screening and management of patients with uncontrolled hypertension in a South African cohort. The successful candidate will be expected to produce peer-reviewed publications from the research and will be expected to participate in the activities of BRIP, including the co-supervision of a MSc or Ph.D. student.
MSc (2020-2021) Scholarship for 2020-2022 - 12 February 2020 23:59
Biomedical Research and Innovation Platform, Parow, Cape Town
A South Africa – Taiwan Joint Science and Technology Research Cooperation funded by the National Research Foundation of South Africa has made available a 2-year MSc scholarship. The primary aim of the proposed research is to evaluate the lipid lowering, antidiabetic and anti-inflammatory effects of synthetic aspalathin, a flavonoid isolated from rooibos. The study will employ advanced cell culture and animal models in combination with proteomics and genomics, to identify specific biological pathways relevant to aspalathin as a potential druggable antidiabetic and lipid lowering drug candidate.
MSc Scholarship - 12 February 2020 23:59
Biomedical Research and Innovation Platform, Parow, Cape Town
Applications are invited for an NRF-Funded MSc scholarship which forms part of the project “Developing an advanced cell culture model for pancreatic beta cells” The primary objective of the MSc study will be to determine the differential physiological response(s) of 2D and 3D cultured pancreatic beta cells to nutritional stimuli (i.e. glucose, long- and short- chain fatty acids, amino acids). Advanced 3D culture will be used to produce functional pseudo-islet clusters that mimic normal pancreatic beta cell physiology and are able to respond to nutritional stimuli relevant to the development of diabetic pathology. The successful applicants will have the opportunity to work with a dynamic research group within the Biomedical Research and Innovation Platform, South African Medical Research Council (SAMRC) and will conduct research that is relevant in South Africa using state-of-the-art technologies.
MSc (2020-2021) and Ph.D Scholarship for 2020-2022 - 12 February 2020 23:59
Biomedical Research and Innovation Platform, Parow, Cape Town
A research collaboration between the South African Medical Research Council (SAMRC), BioPharm and Polytechnic University of Marche (UM), Italy has made available a 2-year MSc and a 3-year Ph.D. fellowship. The fellowship positions will form part of a multi-disciplinary NRF-CPRR funded study. The primary objective of this partnership is to test the ability of a BioPharm product to protect the heart against various chemical (Doxorubicin) or diabetes-induced insults. Accordingly, literature suggests that extracts of G. africana may have therapeutic effects that could modulate cardiac bioenergetics having a beneficial effect on the cardiac muscle. However, to date, no studies have been done investigating the ability of isolated compounds from G. africana to protect the myocardium against diabetes or doxorubicin-induced stress. As such, the ability of these compounds to protect the myocardium will be tested in both an H9c2 cells as well as an in a Wistar rat model. The successful candidate will be registered at the University of Stellenbosch and based at the SAMRC in Cape Town.
MSc Scholarship - 12 February 2020 23:59
Biomedical Research and Innovation Platform, Parow, Cape Town
Applications are invited for an NRF-Funded MSc Scholarship on the interplay between maternal one-carbon metabolism and epigenetic regulation of cardiac energy expenditure in offspring. The overall aim of the proposed study is to determine the extent to which intrauterine exposure to an obesogenic environment affect epigenetic regulation (particularly DNA methylation) of genes involved in postnatal cardiac energy metabolism and functional outcomes. It entails using an in vivo rat model to identify high fat high sugar diet-induced changes in one-carbon metabolism (a pathway that provides methyl groups for DNA methylation) and the extent to which this metabolic shift affect fetal programming of cardiac energy metabolism as well as metabolic syndrome at adulthood. Simultaneously, the role of methyl donor nutrients (select micronutrients) in ameliorating the observed changes will be assessed; the study intends to explore dietary fortification of nutrients that are abundantly found in green leafy vegetables. Understanding these dynamics could provide a platform through which low risk and cost-effective prenatal dietary strategies may be developed to reduce premature mortalities associated with adult cardiovascular complications.
MSc (2020-2021) and PhD (2020-2022) scholarships - 12 February 2020 23:59
Biomedical Research and Innovation Platform, Parow, Cape Town
A research collaboration between the South African Medical Research Council (SAMRC) and the University of Pretoria funded by the National Research Foundation of South Africa (NRF) has made available 2-year MSc and 3-year PhD scholarships for a study entitled “Diabetes in pregnancy: The identification of epigenetic signatures”. The study aims to use DNA methylation and microRNA profiling to identify epigenetic signatures of glycaemic control and maternal and foetal health in pregnancies complicated by diabetes. The identification of novel epigenetic signatures of glycaemic control and pregnancy outcomes may facilitate tighter glucose control during pregnancy and decrease adverse pregnancy outcomes.